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Group Members

Prof. Marcelo Ganzarolli de Oliveira

Principal Investigator

ORCID

University of Campinas (M.S.), University of Campinas (Ph.D.), University of Southampton (Post-doc)

 

     Prof. Marcelo Ganzarolli de Oliveira received his Ph.D. in Science from the University of Campinas (UNICAMP) in São Paulo state, Brazil, in 1992, where he was appointed Assistant Professor in 1987. After his doctoral studies he served as Visiting Research Fellow at the Chemistry Department of the University of Southampton, UK, from 1993 to 1995.

     He was appointed Associate Professor (2000) and Full Professor (2014) in the Physical Chemistry Department of the Institute of Chemistry of UNICAMP, where he currently develops his studies aimed at the preparation of polymeric biomaterials for the controlled release of nitric oxide (NO).

Current Members
  • Post-docs

Rayane da S. Vale

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Federal University of São Carlos, 2020 (Ph.D.)

     Her project is focused on developing fully absorbable, nitric oxide-releasing intracoronary stents. These stents are made from polynitrosated polyesters, specifically poly(lactic acid), poly(caprolactone), or their blends. By employing techniques such as 3D printing and electrospinning, she aims to create stents that not only fully bioabsorb but also release nitric oxide locally, providing potential antithrombotic and pro-endothelial effects.

FAPESP Fellowship (2024).

Eronildo A. P. Junior

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University of Campinas, 2023 (Ph.D.)

    His project aims to develop new polymeric biomaterials, based on methacrylated hyaluronic acid and thiolated gelatin, for cardiovascular regenerative medicine, with the goal of treating coronary artery occlusion or stenosis through the 3D printing of innovative photo-reactive hydrogels that promote the controlled release of nitric oxide.

FAPESP Scholarship (2024)

  • Ph.D. candidates

Herllan V. de Almeida

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University of Campinas, 2022 (M.Sc. in Inorganic Chemistry)

  His project aims to synthesize new organic-inorganic hybrid resins for 3D printing of NO-releasing blood contact devices. We will create polysilsesquioxanes and poly(2-hydroxyethyl methacrylate) based devices using Digital Light Processing (DLP) 3D printing technology.

CNPq Scholarship (2022)

Mateus P. Bomediano

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University of Campinas, 2021 (B.S. in Chemistry)

     His project is focused on the development of 3D printed vascular prostheses based on nitric oxide-releasing hydrogels. Hydrogels functionalized with photocrosslinkable groups will be coated with polydopamine improving the biocompatibility of the constructs for biomedical applications. 

 

FAPESP Scholarship (2022)

Elizaura H. C. Silva

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Federal University of Maranhão, 2020 (M.Sc. in Analitical Chemistry)

 

      Her project is focused on developing perfusable nitric oxide-releasing 3D printed vascular prostheses. Photocurable polymeric resins will be synthesized and two distinct 3D printing techniques, digital light processing and needle extrusion, will be used to fabricate biocompatible constructs that might be useful for the treatment of several cardiovascular diseases.

CNPq Scholarship (2021)

Past Members

Laura C. E. da Silva

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University of Campinas, 2014 (M.Sc.)

University of Campinas & Lund University (internship), 2018 

 

 

 Her projetct involves the preparation of multilayered hybrid nanoparticles made up of poly(hydroxyethyl methacrylate) and polysilsesquioxane for the localized co-delivery of nitric oxide (NO) and antitumoral drugs. Self-organized and multicomponent hydrogels fot the topical NO release will also be produced with this polymeric system. This project is being developed under collaboration with Prof. Alexander Zelikin from Aarhus University - Denmark.

 

FAPESP Fellowship (2019)

 

Daniele M. Catori

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State University of Maringá (M.Sc.)

     Her project concerns the development of injectable gels that are able to locally deliver nitric oxide for the regeneration of cartilaginous tissue. Absorbable hydrogels made up of hyaluronic acid and non-absorbable hydrogels made up of poly(vinyl acetate) will be prepared by in situ photopolymerization as well as 3D printing. 

CAPES Scholarship (2019)

Marcos V. Lorevice

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Federal University of São Carlos, 2015 (M.Sc.)

Federal University of São Carlos & Paris Diderot University  (internship), 2019 

 

 

 His project involves the development of chemically modified polysaccharides (pectin and chitosan) containing bivalent ions and/or methacrylate groups as well as nitric oxide-releasing end-groups for preparing novel biocompatible and 3D printable hydrogels resins that result in nitric-oxide releasing devices with tailored mechanical properties that are suitable for wound healing applications.

 

FAPESP Fellowship (2021)

 

Matheus F. de Oliveira

Federal Fluminense University (B.S.)

     His project aims to the development of fully absorbable and nitric oxide (NO) releasing intracoronary polyester stents. It involves the investigation, synthesis, casting, and evaluation of polynitrosed polyester NO donors, pure and in blends, to try and provide the stent with a complete bioabsorption property and with localized release of NO, which in turn displays antiplatelet, anti-restenotic and pro-endothelial actions.

FAPESP Scholarship (2017)

Murilo I. Santos

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University of Campinas (M.S.)

      His project involveed the development of photocrosslinkable hydrogels based on poly(ethylene oxide)-poly(propylene oxde)-poly(ethylene oxide) triblock copolymers (Pluronics®) for Digital Light Processing (DLP) 3D printing. The printed hydrogels were loaded with NO donors and their biological action will be investigated. 

Co-supervision with Prof. Maria do Carmo Gonçalves Institute of Chemistry (Unicamp) - (08/2018 - 03/2020)

CAPES Scholarship

 

Guilherme Fadel Picheth - 2017 - 2018

His project involved the synthesis of Pluronic F127 triblock polymers containing end-group modifications to release nitric oxide. The project´s goal was to preserve the polymer’s thermo-sensitivity and simultaneously provide activable NO-releasing moieties for wound healing applications. 

 

Mathilde Champeau - 2015 -2016

Her project was devoted to the synthesis of poly(acrylic acid)/PEO-PPO-PEO hydrogels charged with a nitric oxide donor. The hydrogels were molded as membranes and used in topical applications for improving wound healing. The project involved a collaborative work with the Faculty of Medical Sciences at University of Campinas, UNICAMP.

 

Patricia Taladriz-Blanco – 09/2013-04/2015

 

Chiara Montemurro – 04/2013-01/2015

 

Rafael Vercelino – 04/2010-01/2013

 

Kamila Cristina Silva – 11/2011-11/2012

 

Amedea Barozzi Seabra – 11/2005-07/2008 and 04/2010-03/2011

 

Regiane da Silva Gonzales – 08/2008-07/2009

 

Rodrigo Silveira Vieira – 06/2008-03/2009

  • Doctorate (Ph.D)

Scheila Alves - 03/2014 - 2017

 

Victor Baldin – 03/2011-06/2016

 

Marília Meira Dias – 03/2007-02/2012

Co-supervision with Prof. José Barreto Campello Carvalheira – Faculty of Medical Sciences (Unicamp)

 

Gabriela Freitas Pereira de Souza – 02/2008-07/2011

 

Maíra Martins de Souza Godoy Simões – 08/2006-06/2011

 

Rogério Côrte Sassonia – 07/2004-10/2009

 

Regiane da Silva Gonzalez – 03/2005-07/2008

 

Fernanda Ibanes Simplício – 03/2003-03/04/2007

 

Amedea Barozzi Seabra – 03/2003-01/2006

 

Silvia Mika Shishido – 03/1998-16/04/2003

 

Marlus Pinheiro Rolemberg – 09/2000-07/2002 

Co-supervision with Prof. Maria Alvina Krähenbühl – Faculty of Chemical Engineering (Unicamp)

 

 

  • Master (M.S.)

Yuliana Pérez Sánchez - 03/2017 - 02/2019

 

Alexandre Dias Barbosa - 08/2016 - 08/2018

 

Flávia Mesquita Cabrini - 08/2016 - 05/2018

 

Thatiane Cristine Camargo Marini – 01/2014-10/2016

 

Marcelo F. de Azevedo Silva – 08/2012-09/2016

 

Vicente Gomes de Oliveira – 08/2014-09/2016

 

Sarah De Marchi Lourenço – 07/2013-04/2015

 

Fernanda Seabra Schanuel – 03/2012-02/2015

Co-supervision with Prof. Andréa Monte Alto Costa – Rio de Janeiro State University (UERJ)

 

Ana Beatriz Manzano Nascimento – 08/2012-11/2014

Co-supervision with Prof. Dra. Carolina Vautier Teixeira Giongo – Federal University of São Paulo (Unifesp)

 

Raphael Henrique Marques Marcilli – 08/2012-10/2013

 

Maíra Martins de Souza Godoy Simões – 11/2004-06/2006

 

Alessandro Correa Prudente dos Santos – 03/2008-03/2010

Co-supervision with Prof. Cássio Luís Zanettini Riccetto – Faculty of Medical Sciences – Unicamp

 

Regiane da Silva Gonzalez – 03/2004-01/2005

 

Lais Calixto Santos – 08/2001-09/2003

 

Amedea Barozzi Seabra – 03/1999-02/2001

 

Silvia Mika Shishido – 03/1996-06/1998

 

 

  • Research Trainees

Giovana Bosso Romano

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University of Campinas (B.S.) - current

     Giovana is working on the light-assisted 3D printing of organic-inorganic hybrid hydrogels in which S-nitrosoglutathione (GSNO), an endogenous NO-donor, is incorporated after printing to promote NO-relasing properties useful for several biomedical applications.

FAPESP Scholarship (2021)

Yasmim R. Lopes

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University of Campinas (B.S.) - current

      

Yasmin worked on the coating of intracoronary stents and catheters with photopolymerizable methacrylated poly(dodecanediol citrate) and nitric oxide donors to improve blood compatiblility. This project was under collaboration with Prof. Melissa Reynolds, Colorado State University - United States of America.

 

FAPESP Scholarship (2018)

Giovanna J.V.P dos Santos

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University of Campinas (B.S.) - current

     Giovanna was related to the development of bioabsorbable and biocompatible membranes anchored with naturally occurring nitric oxide donors in the human body. These membranes are being employed to accelerate the reepithelialization rate of skin wounds. This project was under collaboration with Prof. Cécile Dreiss, King´s College London - United Kingdom.

 

FAPESP Scholarship (2016)

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Marina F. Maximo

University of Campinas (B.S.) - current

     Marina was based on the development of polu(N-isopropyl acrilamide) (PNIPAAM) membranes containing anchored nitric oxide donors. These membranes are being employed to the prolonged NO delivery in skin wounds. 

 

Leonardo Pinheiro Giglio - 08/2016 - 08/2018

 

Lucas Militão - 11/2015 - 10/2016

 

Amanda Carrico – 02/2016-08/2016

 

Karen Slis Raggio Santos – 07/2013-12/2014

 

Adriana Pereira Lopes Limeira – 02/2012-07/2013

 

Murilo Metzger Denny – 01/2014-12/2014

 

Caroline Simões Pereira – 06/2011 a 05/2012

 

Letícia Marques da Silva – 12/2012-08/2013

 

Elisa Silva Ferreira – 01/2010-07/2012

 

Arthur Teixeira Melo – 08/2011-11/2012

 

Amanda Osteno Lino – 05/2011-09/2012

 

Natália Vance – 01/2011-06/2011

 

Cybele Ribeiro Moura – 12/209 a 12/2010

 

Bruno Morandi Pires – 04/2009-07/2011

 

Marcela Gennari – 10/2007-09/2008

 

Flaviane Alves dos Santos – 03/2009-12/2009

 

Joseph Elias – 07/2008-08/2008

 

Jaqueline Priscilla Denadai – 05/2007-11/2008

 

Gabriela Freitas Pereira de Souza – 04/2004-03/2007

 

Thiago Costa Ferreira Gomes – 01/2005-12/2005

 

Juliana Correia Bergallo Vaz – 09/1999-09/2000 and 03/2001-03/2002

Co-supervision with Prof. Rahoma Sadeg Mohamed – Faculty of Chemical Engineering – Unicamp

 

Amarildo Grando – 05/1999-12/2000

 

Dirnei Aparecido Machado – 02/1995-03/1996

 

Fabiana Ocampos – 09/1995-10/1996

 

Ricardo Ganães Cosso – 06/1991-11/1991

 

Euler Martins Lage – 06/1990-04/1991

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